Iran's Agriculture Minister Mahmoud Hojjati and his Ghanaian counterpart Fiifi Fiavi Kwetey signed a document to boost cooperation.
In the meantime, Nayereh Pirouzbakht, head of Iran's National Standards Organization and his counterpart from Ghana Hanna Tetteh signed the second cooperation document.
Ghana's President John Dramani Mahama is in Tehran on an official visit to hold talks with senior Iranian officials.
Heading a high-ranking politico-economic delegation, Mahama arrived in Tehran on Saturday night at the invitation of his Iranian counterpart Hassan Rouhani.
The Ghanaian president was welcomed at Tehran Mehrabad airport by Minister of Agriculture Mahmoud Hojjati who chairs the Iranian side of Iran-Ghana joint commission.
President Rouhani officially welcomed his Ghanaian counterpart on Sunday morning.
The visit is the first by a Ghanaian president to Iran in 37 years.
Mahama is set to hold talks with Leader of the Islamic Revolution Ayatollah Seyyed Ali Khamenei, his Iranian counterpart as well as Parliament (Majlis) Speaker Ali Larijani.
On Monday, he will also attend a trade and economic meeting of businessmen and enterprises from the two countries.